DOI: 10.36347/sjams.2020.v08i10.031

Pages: 2375-23781

Introduction: Osteoarthritis (OA) knee is the most prevalent degenerative joint disease in the relatively elderly population. It is a leading cause of pain and disability in most countries worldwide. Aim of the study: To determine the effects of PRP in patients with OA knee. Material & Methods: A total 60 patients with OA knee were selected irrespective of sexes seeking treatment in the department of Physical Medicine and Rehabilitation, BSMMU, Dhaka and also referred from various outpatient departments of BSMMU and also general practitioners outside the hospital. The diagnosis of OA knee was confirmed by history, clinical examination, laboratory and radiological findings. They were divided into two group from radiological grading (Kellgren-Lawrence grade-I-III).In group-A patients were given intraarticur steroid, exercise and ADL instructions and group-B were treated with Intraarticur PRP, exercise and ADL instruction. All the patient availed 6 follow up at two week interval and two injection were given at 1st and 7th week. In every follow up patients were assessed by Visual analogue scale (VAS) and WOMAC score. All data were analyzed statistically by using the SPSS (version-21) for windows. Both paired and unpaired Student’s ‘t’ test and Chi-squired test was done as required, to see the level of significance. The results were expressed as mean standard deviation (SD) and p<0.05 was considered as the level of significance. Results: In both groups, majority of the participants had osteoarthritis in right knee joint. There is no statistical significance regarding knee involvement between two groups as the p-value is not significant. Table-4 showed the radiological grading of two groups. In both the groups most of the patients were enrolled in grade –II (>50%) .There is no statistical significance between the two groups. In comparison between two groups, it was found that there was no significant difference in improvement up to Wl to W9 scores, but difference of.....