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Scholars Journal of Applied Medical Sciences | Volume-8 | Issue-11
Histopathological and Clinical Correlation of Hyperpigmented Skin Lesions
Dr. Sneha Ravindran, Dr. Kalla Ravi Teja, Dr. Arun Kumar SP, Dr. Jonathan Arnold, Dr. Balaji S
Published: Nov. 11, 2020 |
310
630
DOI: 10.36347/sjams.2020.v08i11.007
Pages: 2472-2477
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Abstract
Introduction: The spectrum of clinical disease related to hyperpigmented lesion is wider. The most common hyperpigmented skin lesion is lichen planus and its variants. Histopathological examination helps to derive an accurate tissue reaction. Pathologic examination often serves as a confirmative diagnosis for skin lesions. The histology-based treatment will be helpful for establishing a standardized management for hyperpigmentary skin lesions. Materials and Methods: A total of 100 patients with hyperpigmented punch skin biopsy lesions in all age groups following inclusion and exclusion criteria is taken and examined for histopathological correlation from the Department of Pathology. Result: In this study of hyperpigmented skin lesions the maximum number of cases 45 (45%) were those of classical Lichen planus and its variants, followed by 12% of eczematoid dermatitis, 8% of PMLE, 7%of DLE, 6% of lichen simplex chronicus, 7% of post inflammatory hyperpigmentation, 3% of prurigo nodularis, 4% of prurigo simplex, morphea 4%, acne 3%, and 1% of erythema dyschromium perstans. 90% cases show histopathological correlation and 10% cases were diagnosed only on histology based. Conclusion: Lichen planus and its variants are most common hyperpigmentary skin lesions found in the study population. The pathologist ability to render an accurate diagnosis depends on the available clinical evaluation details.