DOI: 10.36347/sjams.2020.v08i11.013

Pages: 2504-2507

Introduction: The term serous effusion refers to the fluid collected in the three serous cavities namely pleural, peritoneal and pericardial. Serous effusions form an important source of useful diagnostic information in clinical practice. Pleural effusion cytology is the simplest definitive method available to diagnose the disease, which are the causes of pleural effusion. Diagnostic cytology depends on the fact that cells exfoliated or collected from a tissue surface reflect changes occurring in the underlying tissue. Materials & Methods: This study was conducted for a period of two years. The study was prospective based on cases admitted as in-patients. Total 235 cases were taken, and the ages of patients ranged from 14 years to 70 years and the group consisted of 170 male patients and 65 female patients. Results: Out of the total 235 patients with pleural effusion 196 were non-malignant and 39 were malignant. Out of the 235 effusion samples the majority were of non-specific compromising 47%. Next common was specific inflammation effusion comprising 33% next was malignant effusion comprising 17%. The unconfirmed effusion 3% were at the end of work up remained in conclusive. Conclusion: The present study demonstrated that the most useful single test in establishing the diagnosis of pleural effusion is the pleural fluid cytological study (60%). In conclusion, an ADA level of pleural fluid is a non-invasive, inexpensive and repeatable test that provides the results quickly. This study indicates that the ADA levels of the pleural fluid can be used with high diagnostic rates in the diagnosis and exclusion of the tuberculosis in patients whom the pleural tissue could not be obtained with various causes in the differential diagnosis of Tuberculosis and Malignant effusions, and those with waiting for the laboratory outcomes of the pleural tissue. In non-biopsy based Tuberculosis diagnosis a threshold of 47 IU/dl is most useful.