DOI: https://doi.org/10.36347/sjmcr.2024.v12i11.009

Pages: 1869-1874

Introduction: Ectopic secretion of Adrno-Cortico-Tropic-Hormone (ACTH) is a rare cause of endogenous hypercorticism. Locating the tumour responsible remains the main and most difficult stage in its management. Case report: We report the case of a 33-year-old male patient admitted with rapidly progressive flare hypercorticism related to ectopic ACTH secretion. Given the rapid worsening of the clinicobiological picture and the impossibility of locating the causative tumour, a bilateral salvage adrenalectomy was performed. Discussion and Conclusion: The small size of the tumours responsible for ectopic ACTH secretion sometimes makes them very difficult to localise, necessitating the use of symptomatic rescue treatments.