DOI: https://doi.org/10.36347/sasjs.2024.v10i11.014

Pages: 1256-1259

Sarcomatoid carcinoma is a rare and highly malignant tumor characterized by a dual histological differentiation with both epithelial and mesenchymal components, constituting less than 1% of all head and neck carcinomas and predominantly affecting males in their fifth to seventh decades of life. We present the case of a 60-year-old man with a six-year history of poorly managed left hemiplegia, who developed a large, aggressive, and bleeding mass in the left upper lip that extended to the maxilla and palate, accompanied by bone destruction and confirmed lymph node metastasis through biopsy. Due to the advanced stage of the disease and delayed consultation, surgical excision was not feasible, leading to a reliance on palliative treatment. This case highlights the diagnostic challenges of sarcomatoid carcinoma, often associated with delayed recognition, poor prognosis, and high mortality rates due to local and distant recurrences. Increased awareness and early diagnosis are critical for improving treatment outcomes. Further research is needed to establish standardized management protocols for this aggressive tumor.