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Scholars Journal of Medical Case Reports | Volume-12 | Issue-11
Renal Involvement in Sjögren Syndrome: A Case Report
A. K. M. Shahidur Rahman, Ferdous Jahan, Md. Rezaul Alam, Syed Fazlul Islam, Md. Kabir Hossain, Md. Saiful Islam, Tahmidul Islam, Mohammad Nazrul Islam, Debabrata Ghosh, A. H. Hamid Ahmed
Published: Nov. 25, 2024 |
119
49
DOI: https://doi.org/10.36347/sjmcr.2024.v12i11.030
Pages: 1967-1973
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Abstract
Sjögren syndrome (SS) is an autoimmune disorder that characterized by chronic inflammation of exocrine glands. However extra-glandular involvement is sometimes observed. The onset of Sjögren syndrome is insidious and its clinical manifestations are extremely diverse. Lymphocytic infiltration and tissue damage of the affected organs are the histopathological features in Sjögren syndrome. In the cases of renal involvement, tubulointerstitial nephritis (TIN) followed by glomerulonephritis are frequently found in renal biopsies. The prognosis of glomerular disease in Sjögren syndrome is usually favorable but the risk of developing chronic kidney disease (CKD) is remains high among patients with TIN.