DOI: https://doi.org/10.36347/sjmcr.2024.v12i12.040

Pages: 2170-2172

This case report presents a 67-year-old male with a neck lump, initially suspected of being a malignancy, later diagnosed with IgG4-related disease (IgG4-RD). The patient presented with a non-mobile, firm mass on the right side of the neck, with no associated symptoms such as dysphagia or pharyngeal discomfort. His diagnostic journey included imaging, fine needle aspiration, and histopathological analysis, ultimately revealing characteristics consistent with IgG4-related disease. This condition, though rare, should be considered in the differential diagnosis of neck lumps, particularly in the primary care setting, where early recognition can significantly influence treatment outcomes. The patient was treated with glucocorticoids, and multidisciplinary management was needed in such cases. The case highlights the importance of distinguishing IgG4-RD from other common causes of neck lumps, such as infections or malignancies, and underscores the role of histology in confirming the diagnosis.