DOI: https://doi.org/10.36347/sjmcr.2025.v13i01.004

Pages: 28-35

Cervical cancer is a pattern of cancer preceded by a long period of disease at the pre-invasive state, which is characterized on a microscopic level by a broad spectrum events ranging from cellular atypia to varying degrees of dysplasia or neoplasia cervical intraepithelial (CIN), before eventually progressing to invasive cancer. Thus, secondary prevention of cervical cancer is based on screening, diagnosis and treatment of cervical intraepithelial neoplasia, with post-treatment follow-up adequate. Material and Method: The objective of our work is to determine the epidemiological profile patients treated for cervical dysplasias, the modalities of diagnosis, the search for the correlation between cytology and histology as well as therapeutic management and monitoring methods. Our study is a retrospective analysis of 58 cases of low- and high-grade CIN, recruited and treated in the Gynecology-Obstetrics II department of the Hassan II University Hospital in Fez, during a period of 04 years from January 2012 to January 2016. Result: The average age of our patients was 50.10 years with extremes of 31 and 78 years. Almost all of the patients were multi-gesture (93.10%). 90% of the patients were symptomatic, with symptoms of metrorrhagia in 76% of cases, pelvic pain in 15% of cases and leucorrhoea in 9% of cases. The cytology study by FCV showed a predominance of ASC-H lesions (41.40%), followed by AUC-US (31%), then LSIL (27.60%). Colonoscopic classification a posteriori revealed 62% of TAG2. The histological study on colpo-guided biopsy had shown a predominance of high-grade lesions (CIN2+CIN3) which represented 69% of cases. Low-grade lesions (CIN1) accounted for 31% of cases. Conservative conization therapy was considered in all patients. 49 conizations were performed with a cold scalpel, while only 9 were performed with a diathermic handle. The final histopathological study showed a predominance of high-grade lesions which represented 70% of cases, low-grade .........