DOI: https://doi.org/10.36347/sjmcr.2025.v13i01.006

Pages: 39-45

Multifocal choroiditis is a rare affection of unknown etiology, and tuberculosis is one of its numerous causes. Our study highlights the need to look for tuberculosis in case of multifocal choroiditis, even without clinical history or signs suggestive of pulmonary tuberculosis. We present the case of an immunocompetent patient with isolated multifocal choroiditis, which strongly suggests tuberculosis. The positive diagnosis was made based on the positivity of the QuantiFERON-TB® Gold immunoassay, given the low sensitivity and specificity of conventional diagnostic methods. Further tests revealed a positive tuberculin skin test in this patient. The plasma interferon assay represents a valuable new tool in diagnosing primary ocular tuberculosis. Although the disease is presumed to be autoimmune, our patient responded well to a carefully managed nine-month course of anti-tuberculosis and anti-inflammatory treatment.