DOI: https://doi.org/10.36347/sjams.2025.v13i01.009

Pages: 43-50

Introduction: Toxoplasmosis is a common infection with a worldwide distribution. It affects homeotherms and has a significant impact on human health, particularly in cases of pregnancy or immunodepression. The aim of this study was to assess the seroprevalence of this parasitosis and determine the main risk factors associated with positive serology in pregnant women in the Fès-Meknès region. Material and Method: This is a cross-sectional study carried out between April 2019 and March 2020, involving 285 pregnant women from the Fès-Meknès region, followed up in the gynecology department of the Moulay Ismail Military Hospital in Meknès and in the two gynecology-obstetrics departments of the Hassan II University Hospital in Fès. Serological detection of immunoglobulin G was performed to estimate the seroprevalence of toxoplasmosis. Results and Discussion: The seroprevalence of toxoplasmosis was 49.1%, suggesting that a significant proportion of women are non-immune and therefore at risk of congenital toxoplasmosis. Seroprevalence increases with age and illiteracy, and is higher in urban than in rural areas. Conclusion: Our study highlights the usefulness of preconception screening for toxoplasmosis, the value of serological surveillance of non-immune women during pregnancy, and the importance of implementing educational programs for women of childbearing age to reduce the burden of abortion, fetal death and infant sequelae attributable to this parasitosis.