DOI: https://doi.org/10.36347/sasjm.2025.v11i01.009

Pages: 33-36

Introduction: Contrast-induced nephropathy (CIN) is a common complication of coronary angiography due to the nephrotoxic effects of contrast agents. This study aims to identify the risk factors for acute kidney injury (AKI) in patients undergoing coronary angiography. Methods: We conducted a retrospective study over 8 months, from January 2024 to August 2024, in the cardiology department of the Avicenna Military Hospital in Marrakech. All patients received a water-soluble, non-ionic contrast agent. Serum creatinine levels were measured before and 24 to 72 hours after the procedure. Statistical analysis was performed using SPSS software version 21. Results: The mean age of the study population was 65.24 ± 8.78 years, with a male predominance (male-to-female ratio: 4.62). Five patients (11.11%) developed CIN. Among them, 33.3% had diabetes and hypertension, 20% had a history of pre-existing cardiac disease, and 27.9% had used nephrotoxic drugs. Two patients (4.4%) received hydration with saline solution, and one patient (2.2%) received hydration with both saline and bicarbonate solutions. Statistical analysis identified a significant association between the development of CIN and two factors: age (p = 0.014) and hypertension (p = 0.036). Conclusion: Larger studies are needed to better identify patients at risk for CIN and implement effective preventive measures for patients undergoing coronary angiography.