DOI: https://doi.org/10.36347/sjams.2025.v13i01.035

Pages: 223-228

1. Background: Holmium Laser Enucleation of the Prostate (HoLEP) is a modern surgical approach for treating benign prostatic hyperplasia (BPH), known for its minimal invasiveness, reduced complication rates, and faster recovery times compared to traditional methods. It is particularly advantageous for patients with large prostate volumes, providing effective symptom relief and enhancing quality of life. This study aims to evaluate the safety, efficacy, and clinical outcomes of HoLEP in male patients with BPH. Objectives: To assess the safety, effectiveness, and clinical outcomes of HoLEP in male patients with BPH. Methods: The prospective observational study was conducted at Square Hospital, Dhaka, Bangladesh, involving 106 male patients diagnosed with BPH who underwent HoLEP between July 2014 and October 2018. Data were collected on demographic characteristics, surgical outcomes, and postoperative recovery. Statistical analysis was performed using SPSS, with descriptive statistics applied to continuous variables and categorical data. Ethical approval was obtained, and informed consent was provided by all participants in accordance with ethical guidelines. Results: The study included 106 male patients (mean age 65 ± 5.6 years), with the majority (60%) being retired and 30% employed as professionals. The mean operation time was 90 minutes, with an average enucleated tissue weight of 45 grams. Postoperative catheterization was required for 25-48 hours in 50% of patients, and the average hospital stay was 2–4 days. Dysuria was reported in 5% of patients, while 95% were symptom-free at the one-month follow-up. International Prostate Symptom Score (IPSS) improvements of more than 10 points were observed in 75% of patients. Conclusion: HoLEP is a safe and effective surgical treatment for BPH, offering minimal complications, short recovery times, and significant improvement in symptoms. This study confirms HoLEP as a promising option for patients with BPH, especially ...