DOI: https://doi.org/10.36347/sasjs.2025.v11i01.017

Pages: 86-88

Breast cancer is the most common cancer in women and is, therefore, a major public health problem. Among the different types of breast cancer, breast carcinoma in situ occupies a special place because of its pre-invasive nature. Ductal carcinoma in situ (DCIS) accounts for 85% to 90% of in situ breast cancers. Their incidence is increasing as a result of widespread screening. Lobular carcinoma in situ remains a rare lesion and is considered to be a cancer risk factor. Diagnosis of this cancer is quite difficult, and treatment is team-dependent, ranging from conservative treatment to mastectomy. The aim of our study was to describe the epidemiological and clinical characteristics of patients with carcinoma in situ isolated within the gyneco-obstetrics II department in Fez, as well as the therapeutic modalities. 19 patients were included; the mean age of our patients was 56 years, with extremes ranging from 34 to 88 years. The average consultation time was seven months; the mode of discovery was dominated by the discovery of a nodule on a breast self-exam in 13 patients (72%), followed by a pathological nipple discharge in 5 and a combination of two in one patient. The average tumor size was 3 cm, with extremes ranging from 1 cm to 5 cm. Combined screening with mammography and breast ultrasound was carried out in all our patients (100%), supplemented by MRI in 4 patients (high breast density) with a view to conservative treatment. Histology was dominated by ductal carcinoma in 17 patients (92%). The surgical procedure was conservative in 5 patients (28%) and radical in 13 (72%). 3 out of the 5 patients who had undergone conservative surgery underwent revision surgery (mastectomy) due to positive surgical margins (60%). 11 (61%) patients benefited from an axillary procedure essentially by sentinel lymph node biopsy which was negative (100%).