DOI: https://doi.org/10.36347/sjams.2025.v13i01.043

Pages: 268-274

Introduction: Spinal anesthesia in obstetrics is indicated for uncomplicated or semi -urgent elective cesarean section outside of labor or during labor and in the absence of an epidural catheter. Although the trend is toward the use of a dose of bupivacaine increasingly weak, the search for the optimal dose remains a permanent concern in our hospital structures. The aim of this work was to compare the clinical effects of two hyperbaric Bupivacaine protocols (7.5 mg versus 10 mg) during spinal anesthesia for cesarean section. Patients and Methods: This is a prospective, descriptive and analytical study, conducted at the regional hospital of Ourossogui over a period of 3 months, involving 42 patients scheduled for cesarean section under spinal anesthesia. The population was divided into two equal groups (G1: 10 mg; G2: 7.5 mg) with random selection without morphological discrimination, according to a regular sequence: G1-G2; G1-G2... Results: The mean age was 24.79 years in our series (23.8 years for G1 and 24.6 years for G2). The following were observed in the 10 mg group (G1): a greater variation in blood pressure, a higher mean consumption of ephedrine, a longer duration of motor blockade and a higher incidence of complications of spinal anesthesia. However, in this group (G1), it was noted that the parturient was more comfortable during the high points (less pain) of the surgery. Furthermore, there was no correlation between the dose of Bupivacaine and the intensity of the motor blockade, as well as the sensory level. We did not record any major complications such as postpartum hemorrhage, maternal or perinatal death. All patients were transferred to hospital at the end of the procedure. Conclusion: In this preliminary work, the dose of 10 mg seems to be preferable due to the absence of major complications and better comfort for the parturient.