DOI: 10.36347/sjams.2021.v09i12.028

Pages: 1934-1938

Background: Hashimoto’s thyroiditis (HT) is the most common type of thyroiditis and is the 2nd most common cause of goiter in iodine deficient areas. The thyroid function may be normal or altered at time of presentation. Anti-Thyroid Peroxidase antibody (Anti TPO) is considered as diagnostic hallmark of HT. On FNAC, Two main cytomorphologic patterns of HT i.e, Classic Hashimoto’s thyroiditis (CHT) and Florid lymphocytic thyroiditis (FLT) are seen This study aims to correlate the cytomorphological variants of Hashimoto՚s thyroiditis with thyroid autoantibody. Materials and methods: This cross sectional study is done for a period of two years starting from August 20018 in the Department of Pathology, Regional Institute of Medical Sciences (RIMS), Imphal. Sixty-five cases of HT diagnosed during the study period are included. The cytological findings, clinical features, serum levels of T3, T4, TSH and Antimicrosomal autoantibody (AMA) titre were the study variables. Statistical analysis: All the data were entered in a database programme and analysed statistically. Results and observations: Hashimoto’s thyroiditis (HT) constituted 16.5% of the total thyroid aspirates (394) during the study period. The main cytomorphologic variants found are 39 cases of classic Hashimoto’s thyroiditis (CHT) (60%) & 26 cases of florid lymphocytic thyroiditis (FLT) (40% The mean age is 33.05 years in HT, 36.1+ 13.2 years in CHT and 29.5+10.8 years in FLT. Maximum cases presented in euthyroid state (41.5%), hypothyroid (38.6%), subclinical hypothyroid (10.8%) and 9.2% in hyperthyroid state. Anti -TPO antibodies positive in 87.2% of CHT and in 65.4% of FLT and is statistically significant with p value of 0.001. Conclusion: Recognition of cytomorphologic variants of HT is important as they have different clinical presentations and biochemical parameters.