DOI: https://doi.org/10.36347/sasjs.2025.v11i02.014

Pages: 184-186

Liposarcoma is a malignant mesenchymal tumor originating from adipose tissue and is among the most common soft tissue sarcomas in adults. However, its occurrence in the upper extremities is rare, leading to diagnostic and therapeutic challenges. This report presents the case of an 83-year-old female patient with a 20 cm, painless, slow-growing mass in the left arm. Imaging studies, including ultrasound and MRI, confirmed the absence of osteomuscular involvement. Surgical resection with wide margins was performed, achieving complete tumor removal without requiring flap reconstruction. Histopathological analysis confirmed free margins. Due to the anatomical constraints of the upper extremities, achieving adequate surgical margins while preserving function is complex. Although surgical excision remains the primary treatment, the risk of local recurrence and metastasis necessitates long-term surveillance. This case underscores the importance of early diagnosis, precise imaging, and a multidisciplinary approach to managing upper extremity liposarcomas, particularly in elderly patients with comorbidities. Further studies are required to refine treatment strategies and improve clinical outcomes.