DOI: 10.36347/sjams.2014.v02i06.134

Pages: 3520-3524

Background: Perfusion imaging is beneficial in the assessment of stroke severity and outcome prediction by measuring ischemic tissue viability. It investigates the correlation between perfusion imaging findings, stroke severity, and three-month functional outcome in patients with acute ischemic stroke. Methods: This prospective observational study included 50 acute ischemic stroke patients. National Institutes of Health Stroke Scale (NIHSS) upon admission was utilized to assess stroke severity. Perfusion imaging parameters, including perfusion deficits, infarct core volume, and mismatch ratio, were analyzed. Follow-up outcomes were ascertained by the modified Rankin Scale (mRS) at three months. Results: Among the patients, 84% exhibited a perfusion deficit, and 56% had an infarct core volume >50 ml. The mismatch ratio was ≥1.8 in 66% of cases. Stroke severity distribution at admission was mild (16%), moderate (50%), and severe (34%). At three months, 54% of patients had a favorable outcome (mRS 0–2), while 40% had persistent disability (mRS 3–5), and 6% died (mRS 6). Larger infarct volumes and lower mismatch ratios correlated with poorer functional outcomes. Conclusion: Perfusion imaging findings correlate with stroke severity and three-month outcome. Volume of infarct core and ratios of mismatch predict strongly. Perfusion imaging has to be implemented in the practice of stroke so that treatment planning and estimation of recovery capacity is possible.