DOI: https://doi.org/10.36347/sjmcr.2025.v13i03.016

Pages: 399-402

Fundic gland polyps (FGPs) are the most common gastric polyps, typically arising in the oxyntic mucosa of the stomach. They are often incidental findings during upper gastrointestinal endoscopy and are usually asymptomatic. FGPs can occur sporadically or in association with familial adenomatous polyposis (FAP). Sporadic FGPs are more prevalent in individuals on long-term proton pump inhibitor (PPI) therapy, suggesting a link between acid suppression and polyp formation. Management strategies depend on the polyp size, number, and histologic features. Small, asymptomatic, non-dysplastic FGPs require no specific intervention, whereas large or dysplastic lesions warrant endoscopic removal and surveillance. This review explores the pathogenesis, clinical implications, and optimal management approaches for fundic gland polyps.