DOI: https://doi.org/10.36347/sasjm.2025.v11i03.009

Pages: 172-178

Introduction: Lupus-Lyell (LL) or lupus epidermal necrolysis is a rare and severe cutaneous clinical form of systemic lupus. Case Report: This article describes the case of a 22-year-old female patient with multiple skin ulcers who was diagnosed with Lupus-Lyell (Lyell-like syndrome). The article also describes the literature review on the diagnosis and treatment of this complex form of lupus disease. Conclusion: LL is a serious pathology whose diagnosis and management are complex, multidisciplinary and associated with therapeutic education.