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SAS Journal of Medicine | Volume-11 | Issue-03
Seronegative Rheumatoid Arthritis in State Phase Manifesting as Rheumatoid Lung Associated with Co-Infection SARS-Cov-2 and Klebsiella Pneumoniae, In a Context of Probable Variable Expression Hypogammaglobulinemia. At the Intersection of Immunology and Infectious Diseases: Case Report and Literature Review
Ibrahima Amadou Dembélé, Stéphane Loique Djeugoue, Kaly Keïta, Mamadou Cissoko, Adama Sinayoko, Pamanta Sory Ibrahim, Seydou Diallo, Sidi Touré, Dongue T Léa Danielle, Korotoumou Traore, Moctar Koné,.
Published: March 15, 2025 |
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DOI: https://doi.org/10.36347/sasjm.2025.v11i03.010
Pages: 179-191
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Abstract
Introduction: Pulmonary involvement during rheumatoid arthritis is frequent, severe, very polymorphic and is very often the site of a viral or bacterial superinfection. Observation: This article describes the case of a 54-year-old diabetic and asthmatic patient suffering from polyarthralgia and long-term fever, who was diagnosed with seronegative rheumatoid arthritis complicated by rheumatoid lung and associated with co-infection SARS-CoV-2 and Klebsiella pneumoniae was diagnosed. The article presents the therapeutic difficulties specific to this case in our context and also reviews the existing literature on the diagnosis and treatment. Conclusion: Rheumatoid lung is a serious and fatal complication of rheumatoid arthritis; a viral superinfection very often worsens the diagnostic prognosis.