DOI: 10.36347/sjams.2020.v08i12.048

Pages: 2938-2944

Aims and objectives: To determine the histopathologic pattern of bladder cancer with pathological staging and grading. Methods: A retrospective study were undertaken from the records of the diagnosed bladder cancer at the Department of Histopathology, National Institute of Kidney Diseases and Urology, Dhaka, during the period from January 2019 to June 2020. Results: A total of 250 histopathologically diagnosed cases of bladder neoplasm were studied. Of the 250 cases, 224 cases (89.6%, n=250) showed malignant bladder neoplasm and 26 (10.4%) benign bladder neoplasm. Male patients were 201 and female 49. Male: female ratio was 4.1:1. The age ranged from 1yaer to 90 years and average 55 years. A total of 151 cases (67.41%) were non-invasive, 41 (18.30%) invasive and rest 32 (14.28%) advanced bladder cancer. Most frequent non-invasive cancer were pTa stage group 121 (54.01%) followed by pT1 stage group 18(8.03%). Most frequent muscle invasive bladder cancer were in pT2a stage group (8.03%) followed by pT2b stage group (4.91%). Most frequent advanced bladder cancer were pT4a 21 (9.37%) followed by 11 (4.91%). TCC was the most frequent 135 (89.40%) followed by SCC 08 (5.30%). TCC with different grades of differentiation were 61 (83.57%, n=73) followed by invasive TCC with squamous differentiation 08 (10.97%, n=73). Conclusion: Histopathologic pattern of bladder cancer, its pathological staging and grading are of great clinical as well as diagnostic and prognostic importance.