DOI: https://doi.org/10.36347/sajb.2025.v13i04.005

Pages: 386-416

Biotechnology has become a revolutionary tool for wildlife conservation, offering novel approaches to counter the unprecedented challenges facing biodiversity today. This paper examines the application of biotechnology, specifically genetic engineering, cloning, and ecosystem restoration, to conserve endangered species and restore degraded ecosystems. Biotechnology, through genetic engineering, enables researchers to transfer disease resistance and reproductive enhancement into vulnerable species, allowing them to survive against global threats such as chytridiomycosis in amphibians. Additionally, it addresses inbreeding and genetic bottlenecks by reintroducing genetic diversity through gene editing and transgenic methods. Cloning, primarily through the use of SCNT, holds promise for the revival of extinct species and the preservation of genetic information. A prime example of the latter is the case of the Pyrenean ibex, which, despite its short-lived success, highlighted the promise that such technology holds and the ethical questions it raises. In addition to species-specific approaches, biotechnology plays a crucial role in restoring the ecosystem. Through genetic modification, stress-resistant plant varieties and beneficial microbial inoculants are engineered to restore degraded habitats, enhance soil fertility, and enable plants to withstand environmental stressors such as drought and salinity. These efforts support the recovery of degraded native ecosystems that have been impacted by urban development, deforestation, and global warming. While acknowledging the limitations and ethical issues, the article emphasises the importance that biotechnology plays as a complement rather than a replacement for conventional methods. Ultimately, by harnessing the power of science, conservation specialists can more effectively counteract biodiversity loss, making ecosystems healthier and the future more sustainable for wildlife.