DOI: 10.36347/sjams.2021.v09i06.004

Pages: 779-785

Background: Human papillomavirus is a necessary but not sufficient cause of cervical cancer all around the world. Vaccination is considered the primary way to prevent cervical cancer. Bangladesh government has been providing a bivalent HPV vaccine containing HPV 16 and 18 for girls aged 10 years old routinely since this year. This study was to observe the predominant serotypes of the HPV virus among Bangladeshi women. Aim of the study: This study was undertaken to identify the most prevalent HPV genotypes in a cohort of patients presenting with gynecological complaints and to evaluate the relationship between HPV-DNA Genotype positivity and associated clinical features. Methods: This was a Descriptive type of Observational Quantitative study. The study was conducted at the Central Hospital, Dhaka, Bangladesh, between Jan 2017 and Jan 2021. During the study period a total of 244 patients were enrolled and analyzed in this study. The data was collected from the prescriptions and reports of the patients who came to the chamber of a renowned gynecologist. The physicians and statisticians analyzed the qualitative and quantitative data. Results: Among the 244 samples collected, 38 patients were positive for HPV genotype; 18(7.44%) of them were genotype 16, 5(2.07%) had genotype 52, 3(1.24%) had genotype 68, 3(1.24% had genotype 51, 2(0.83%) women had 56, 2(0.83%) had genotype 18, 1 each had genotype 39, 45 and 66. Regular cervical cancer screening is strongly recommended even if the women have been vaccinated against HPV, as our vaccine ‘Cervarix1’ will not cover all the genotypes of the HPV found in the cervical sample of the women of our country. Conclusion: HPV infection, the leading cause of cervical cancer, is preventable through vaccination and early detection by screening. This study highlights the need for large-scale research to identify prevalent genotypes in Bangladesh, aiding vaccine selection. Strengthening awareness, vaccination, and regular screening can si