DOI: https://doi.org/10.36347/sjmcr.2025.v13i05.051

Pages: 974-976

Introduction: MORRIS syndrome is a rare hereditary disease causing complete peripheral androgen insensitivity. The aim of this study was to demonstrate the value of imaging in this syndrome through a case in our department. Case Report: This was a 22-year-old female patient with no known medical or surgical history, apart from primary amenorrhea in her 18-year-old younger sister. She was admitted to the Marie Curie Medical Clinic for primary amenorrhea and a desire to conceive. Clinically, the patient had an unambiguous female morphotype of the external genitalia, with well-developed Tanner stage 4 breasts. There was an absence of axillary and pubic hair. There was evidence of uneventful sexual intercourse, confirming the existence of a normal vagina. Suprapubic and endovaginal ultrasound, as well as magnetic resonance imaging, revealed a vaginal canal without visualization of the uterus or ovaries. Molecular genetic testing revealed an XX phenotype. Conclusion: Insensitivity syndrome is a very rare condition, and cross-sectional imaging is central to diagnostic management.