DOI: https://doi.org/10.36347/sjams.2025.v13i05.017

Pages: 1113-1120

Malaria remains a major public health problem worldwide, particularly in sub-Saharan countries such as Mali. The severe form is responsible for high mortality among vulnerable targets such as children under 5 years of age. Several factors that may be associated with this excess mortality need to be known and controlled. For this reason, we initiated the present study, the general objective of which was to study the factors associated with the vital prognosis of severe malaria in children aged 0 to 59 months admitted for consultation at the MPEDERE medical clinic, Farakala commune, Sikasso health district, from January 2022 to December 2023. We conducted a cross-sectional and analytical study with prospective recruitment which was conducted in the said clinic. The results of the study showed us a hospital frequency of severe malaria of 52.47%, with a sex ratio of 1.01 in favor of boys, a mean age of 32.47 ± 16.26 months and a modal age of 36 months. An epidemiological model of factors associated with mortality related to severe malaria in children aged 0 to 59 months revealed that a delay in seeking care beyond 24 hours as well as respiratory distress were factors significantly associated with excess mortality related to severe malaria in children aged 0-59 months (OR = 285.857; 95%CI. OR: 48.931 – 1669.991 and OR = 0.008; 95%CI. OR: 0.001 – 0.069).