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Scholars Journal of Medical Case Reports | Volume-13 | Issue-05
Is Azithromycin a New Treatment Option for Acute Varioliform Lichenoid Pityriasis?
I. El Modafar, M. Aboudourib, O. Hocar, S. Amal
Published: May 16, 2025 | 132 219
DOI: https://doi.org/10.36347/sjmcr.2025.v13i05.052
Pages: 977-979
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Abstract
Pityriasis lichenoides is a rare inflammatory skin condition with acute (PLEVA) and chronic (PLC) variants. There is no standardized treatment, though antibiotics like erythromycin and tetracycline have shown efficacy. This case report describes an 8-year-old with acute varioliform pityriasis lichenoides successfully treated with azithromycin and an H2 antihistamine. The skin lesions resolved within two weeks, leaving transient hyperpigmentation, with no recurrence after two years. Azithromycin’s anti-inflammatory and immunomodulatory properties, combined with favorable pharmacokinetics and tolerability, suggest it as a promising alternative therapy for PLEVA.