DOI: https://doi.org/10.36347/sjmcr.2025.v13i05.065

Pages: 1034-1038

Anorectal mucosal melanoma is an uncommon and highly aggressive form of mucosal melanoma. Its rarity makes clinical diagnosis difficult, and its initial symptoms are generally non-specific, such as rectal bleeding (the most frequent symptom), anal pain or the presence of an anal mass. The prognosis for this disease is generally poor, and its incidence seems to be increasing every year. Anorectal mucosal melanoma often goes undetected and/or is already metastasized at the time of diagnosis. We present a case report of a patient who initially presented with nonspecific symptoms of anemia and rectorrhagia and was later found to have melanoma of the anorectal region. There is a notable paucity of literature on this disease, resulting in a lack of overall understanding of its nature. Most of the information available is in the form of isolated case reports rather than comprehensive studies. Although surgical resection remains the primary treatment approach, the majority of patients (over 80%) will die from distant metastases within five years of surgery. The five-year survival rate for anorectal melanoma is estimated at between 6% and 22%.