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Scholars Journal of Medical Case Reports | Volume-13 | Issue-06
Macrophage Activation Syndrome Complicating Rheumatoid Arthritis: A Case Report
O. Lamridi, O. Naouis, H. Yahyaoui, M. Chakour
Published: June 13, 2025 | 33 34
DOI: https://doi.org/10.36347/sjmcr.2025.v13i06.027
Pages: 1414-1416
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Abstract
Macrophage activation syndrome (MAS) is a rare but potentially fatal complication that can occur during chronic inflammatory diseases such as rheumatoid arthritis (RA). We report the case of a 68-year-old female patient followed for progressive RA with severe joint involvement and subcutaneous rheumatoid nodules, complicated by MAS revealed by febrile pancytopenia. This case highlights the diagnostic challenges related to the non-specific presentation of MAS and emphasizes the importance of rapid management.