DOI: https://doi.org/10.36347/sjmcr.2025.v13i06.052

Pages: 1512-1515

Gardner syndrome is a rare autosomal dominant disorder caused by mutations in the APC gene. It is characterized by a triad of colorectal polyps with a high risk of malignant transformation, soft tissue tumors, and bone lesions, particularly osteomas of the maxillofacial region. Dental anomalies, including supernumerary teeth, odontomas, and dentigerous cysts, are highly prevalent and often serve as early indicators of the disease. The diagnosis is primarily clinical, supported by genetic testing and imaging. While surgical resection may be necessary for symptomatic osteomas, asymptomatic lesions are generally managed conservatively. Early recognition of oral and maxillofacial manifestations is crucial for timely diagnosis, preventive care, and appropriate surveillance, particularly for colorectal malignancies. A multidisciplinary approach involving dental, surgical, and gastroenterological teams is essential for optimal patient management. This study aims to discuss the clinical presentation, diagnostic challenges, and management of maxilla-facial symptoms. We report a case of a patient diagnosed with Gardner syndrome with exophthalmos, treated successfully.