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Scholars Journal of Applied Medical Sciences | Volume-13 | Issue-07
Alcoholic Liver Disease
Dr. Yusrah Khan
Published: July 7, 2025 | 49 36
Pages: 1392-1398
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Abstract
Alcoholic liver disease is a fatal condition and leading cause of morbidity and mortality caused by excessive alcohol consumption with an average weekly intake of 7-14 units for men and 8.75-26.25 units for women. In UK, it is advised not to consume more than 6 pints of beer or 6 medium wine glasses. ALD presents with liver inflammation and decompensation or fibrosis progression along with comorbidities. In advanced stages, patients develop cirrhosis and related complications leading to poor prognosis that can reduce life expectancy and irreversible liver damage. ALD is treatable at early stages with administration of corticosteroids. Recent studies have reported an association between ALD and tumor necrosis factor-alpha, hence latest research focuses on antitumor antibodies. There is a need for effective management and timely identification of this condition especially in males and individuals aged 40-50 years. This article provides a comprehensive insight regarding risk factors, clinical and laboratory features, and treatment of alcoholic liver disease.