DOI: https://doi.org/10.36347/sjmcr.2025.v13i07.015

Pages: 1586-1588

Fusobacterium nucleatum is a rare cause of meningitis in adults, yet it is associated with significant morbidity and mortality. We present a case of meningitis due to Fusobacterium nucleatum in a 28-year-old male with a history of head trauma two years prior, recurrent pneumococcal meningitis, and a cerebrospinal fluid leak. Initial cerebrospinal fluid (CSF) cultures were sterile despite severe inflammatory abnormalities, and the patient was treated with vancomycin and penicillin. His condition worsened neurologically, requiring intubation, mechanical ventilation, and sedation. A subsequent anaerobic culture identified Fusobacterium nucleatum, and metronidazole was added to the treatment. The patient passed away on the third day due to cerebral edema and intracranial hypertension.