DOI: https://doi.org/10.36347/sjmcr.2025.v13i07.021

Pages: 1610-1612

Reporting a rare instance of nasosinusal malignant melanoma is the goal. A 63-year-old patient was seen to have had nasal blockage and recurrent seurosanguinating secretion evolving for 3 months. The diagnosis was proposed by nasosinusa endoscopy, which revealed a malignant process with dark pigmentation. Mucinous melanomas of the nasal cavity and paranasal sinuses are rare and extremely aggressive tumors. In conclusion, mucous malignant nasosinusal melanoma is a rare histological kind that does not exhibit any particular symptoms. Typically, the tumor is gray-blackish and invasive. Histopathological with immunohistochemistry (HMB-45) is the diagnosis. The therapy protocol needs to be examined by a multidisciplinary team and is not codified. The outlook is not good.