DOI: https://doi.org/10.36347/sjet.2025.v13i07.005

Pages: 492-521

The work present in this paper concern the preparation, characterization and biological evaluation of Cu2+, Ni2+, Co2+ and Mn2+ coordinated compound of ligand obtained from o- amino benzoic acid and furfur aldehyde. For the purpose of Schiff base an amino group present in 0-aminobenzoic acid react with furfur aldehyde during the condensation of one mole of furfur aldehyde and one mole of o-amino benzoic acid. Schiff base have ability to chelates through –C=N- functional group with metals. The complex was formulated as ML2 (2:1) type. Fourier transform infrared spectroscopy, solubility and melting point techniques are used to characterized Schiff base ligand and their complexes. Nitrogen, oxygen and Sulphur containing ligands are growing attention due to their vast biological activities and playing vital performance in inorganic field due to diversity of linking of ligand to transition metal. Schiff base metal complexes are identified to act as role for biological active agents like antifungal, anticonvulsant, antiviral, anticancer, antimicrobial and antibacterial agents.