DOI: https://doi.org/10.36347/sasjm.2025.v11i09.013

Pages: 895-897

Crohn’s disease is a chronic inflammatory disorder of the gastrointestinal tract, characterized by segmental and transmural inflammation that may affect any portion of the digestive tract, from the mouth to the anus. In patients undergoing chronic hemodialysis, management is particularly challenging due to drug interactions and renal-related complications. We report the rare case of a 60-year-old man on chronic hemodialysis, admitted for lower gastrointestinal bleeding. Colonoscopy revealed aphthoid ulcers in the terminal ileum, cecum, and descending colon and biopsy confirmed the diagnosis of Crohn’s disease. This case highlights the diagnostic and therapeutic challenges posed by the coexistence of Crohn’s disease and end-stage renal disease, underlining the importance of a multidisciplinary approach to optimize clinical outcomes in this high-risk population.