DOI: https://doi.org/10.36347/sjmcr.2025.v13i10.013

Pages: 2237-2241

Primary cutaneous malignant melanoma of the breast is an exceptionally rare neoplasm, particularly in male patients. Although it shares clinicopathological features with melanomas from other cutaneous sites, its atypical location often complicates diagnosis and staging. Regional lymph node involvement remains the most important prognostic factor in melanoma, making accurate identification of sentinel lymph nodes (SLNs) a critical step in management. We report a rare case of primary cutaneous malignant melanoma of the breast in a male patient. Due to the rarity of this presentation, careful staging was necessary to guide therapeutic decisions. Lymphoscintigraphy was employed for sentinel lymph node mapping. This enabled a targeted sentinel lymph node biopsy (SLNB), avoiding unnecessary axillary lymph node dissection. This case underscores the critical role of lymphoscintigraphy in the staging and management of primary cutaneous malignant melanoma of the breast, especially in male patients. By facilitating precise SLN localization, lymphoscintigraphy improves staging accuracy, supports individualized treatment planning, and reduces the morbidity associated with more extensive surgical procedures. Its integration into the diagnostic workflow is essential for optimizing outcomes in rare and anatomically uncommon melanoma presentations.