DOI: https://doi.org/10.36347/sjmcr.2025.v13i10.030

Pages: 2310-2311

Introduction: Thyroid tuberculosis is a rare form of extrapulmonary tuberculosis. Due to its nonspecific clinical and radiological presentation, it can easily mimic thyroid cancer. Case report: A 55-year-old female presented with a thyroid swelling. Neck ultrasound showed a 26 mm TIRADS V nodule. Total thyroidectomy was performed. Histopathological examination revealed isolated thyroid tuberculosis. Discussion: This case highlights the rarity of thyroid tuberculosis and the diagnostic challenge it poses. It underlines the importance of considering this diagnosis in the differential, especially in endemic areas. Conclusion: Even when clinical and imaging signs suggest malignancy, thyroid tuberculosis should be considered. Histology remains crucial for diagnosis and management.