DOI: https://doi.org/10.36347/sjmcr.2025.v13i10.051

Pages: 2410-2413

Respiratory epithelial adenomatoid hamartoma (HERA) is a benign pseudo-glandular proliferation of the respiratory epithelium, often associated with chronic nasosinus polyposis, it localizes preferentially in the olfactory clefts. Its clinical presentation is non-specific or even atypical. Imaging, based on naso-sinusal CT focusing on the olfactory slits, plays an important role both diagnostically and therapeutically. Diagnosis of certainty is based on histology. Differential diagnosis is mainly represented by inflammatory polyps, inverted papillomas and malignant tumors of the nasal cavity. The treatment of choice for HERA is exclusively surgical, consisting of complete surgical removal of the tumor and its base of implantation, ensuring in the majority of cases an excellent prognosis with no recurrence. Malignant degeneration has not been reported. The aim of our article is to analyze the clinical, therapeutic and evolutionary characteristics of nasal adenomatoid respiratory epithelial hamartomas, based on a case report of a hamartoma discovered in a 74-year-old female patient during exploration for OSA, and a review of the literature.