DOI: https://doi.org/10.36347/sjmcr.2025.v13i10.079

Pages: 2521-2522

Emphysematous pyelonephritis (EPN) is a severe, necrotizing renal infection characterized by gas formation within the renal parenchyma, collecting system, or peri-renal spaces. It is most frequently seen in diabetic or immunocompromised patients and can be life-threatening. We report a case of a 45-year-old male with known prostate cancer and a prior left nephrostomy for moderate hydronephrosis, presenting with febrile abdominal pain. CT confirmed right-sided EPN. This case highlights the importance of early diagnosis and tailored management in high-risk patients.