DOI: https://doi.org/10.36347/sjmcr.2025.v13i10.085

Pages: 2540-2543

Neurogenic Myositis Ossificans (NMO) is a rare form of heterotopic ossification that occurs in approximately 10–20% of patients with severe central nervous system injuries, most commonly after traumatic brain or spinal cord injury. It is characterized by ectopic bone formation within periarticular soft tissues, leading to pain, swelling, and progressive joint stiffness. We report the case of a 54-year-old male who developed a paraplegia after a spine injury. Radiographs revealed early periarticular calcifications that progressively matured into well-organized ossifications on CT, showing cortical and trabecular differentiation without continuity with the adjacent skeleton—features typical of NMO. Laboratory tests showed elevated alkaline phosphatase with no systemic inflammation. The patient was managed conservatively with anti-inflammatory therapy and physiotherapy, resulting in stabilization of the ossifications but no functional recovery. This case illustrates the characteristic imaging evolution of NMO and emphasizes the radiologist’s key role in early diagnosis, differential assessment, and follow-up to guide appropriate multidisciplinary management.