DOI: https://doi.org/10.36347/sajb.2025.v13i10.005

Pages: 1441-1449

Pesticides are chemical or biological agents capable of destroying pests or controlling their growth and reproduction. Long-term exposure could have adverse effects on biochemical parameters. To this end, several parameters were analyzed, namely the subjects' knowledge and attitudes about pesticides, the determination of cholinesterase and transaminase activity, and the measurement of urea and creatinine levels using a Cobas C 111 automated analyzer and a spectrophotometer. Blood samples were taken. All subjects surveyed had a good knowledge of pesticides, and there was a correlation between their knowledge and their practices. The study population consisted of 30 market gardeners and 50 controls. The average age was 59.83 ± 7.751 and 33.56 ± 14.888 for market gardeners and controls, respectively. These analyses showed an average urea concentration of 0.24 ± 0.055 g/l and 0.24 ± 0.0261 g/l, respectively, and creatinine concentrations of 8.76 ± 1.912 mg/l and 8.67 ± 1.470 mg/l respectively in the control group and market gardeners (p>0.05); the mean values of transaminases (TGO) in the control group and market gardeners were 29.12 ± 12.25 IU/l and 16.93 ± 7.900 IU/l respectively (p<0.05); the mean cholinesterase values in the control group were 9584.42±1686.26 U/L and those in the market gardeners were 7590.63± 1606.27 U/L with (p<0.05); the cholinesterase activity of market gardeners was inhibited by 20%. This inhibition does not require any risk mitigation measures, as it is below 40%, which is the biological limit recommended by the WHO.