DOI: https://doi.org/10.36347/sjmcr.2025.v13i10.094

Pages: 2583-2585

The discovery of cerebral calcifications, particularly when incidental, requires a rigorous diagnostic approach to determine their underlying cause. While they are often physiological and age-related, their topography, morphology, and bilaterality are key clues in guiding the diagnosis towards pathological origins such as metabolic or genetic disorders (like Fahr's disease), past infections, vascular issues, or tumors. The non-contrast CT scan remains the gold standard for their detection, but its analysis must be supplemented by an MRI to characterize the adjacent brain parenchyma and, crucially, by a metabolic workup (calcemia, phosphoremia, PTH) to identify or rule out an underlying systemic condition and to guide appropriate patient management.