DOI: https://doi.org/10.36347/sjmcr.2025.v13i10.112

Pages: 2650-2652

Background: Brenner tumors of the ovary are rare fibro-epithelial neoplasms, representing approximately 1–2% of all ovarian tumors. They include benign, borderline, and malignant forms and are characterized by nests of transitional epithelial cells within a fibrous ovarian stroma. Case Presentation: We report a case of a 62-year-old postmenopausal woman who presented with a progressively enlarging abdominopelvic mass. Imaging revealed bilateral solid-cystic ovarian masses without evidence of peritoneal or lymphatic involvement. Serum tumor markers, including CA-125 and HE4, were within normal limits, with a low ROMA score. The patient underwent total hysterectomy with bilateral salpingo-oophorectomy, infracolic omentectomy, and multiple peritoneal biopsies. Histopathology confirmed a benign bilateral Brenner tumor. Discussion: Brenner tumors are usually asymptomatic or present with nonspecific pelvic symptoms. Imaging typically shows solid or solid-cystic masses, sometimes with calcifications. While benign forms have an excellent prognosis and are managed conservatively, malignant and borderline forms are rare and pose diagnostic and therapeutic challenges. Surgical management is guided by the risk of malignancy, with radical surgery reserved for suspected malignant cases. Conclusion: Despite their rarity, Brenner tumors should be considered in the differential diagnosis of ovarian masses. Histopathological examination remains the gold standard for diagnosis.