DOI: https://doi.org/10.36347/sjams.2025.v13i11.001

Pages: 1794-1800

Background: Metabolic syndrome (MetS) and chronic kidney disease (CKD) are major public health concerns globally, with visceral adiposity playing a pivotal role. Sonographic measurement of intra-abdominal fat thickness (IAFT) provides a non-invasive method to assess central obesity, but its relationship with MetS and CKD is not well-studied in South Asian populations. Objectives: To investigate the association of sonographically measured IAFT with MetS and CKD among adults in Bangladesh. Methods: A cross-sectional analytical study was conducted at BIRDEM General Hospital and the National Institute of Kidney Diseases & Urology (NIKDU), Dhaka, from July 2021 to June 2023. A total of 148 adults undergoing abdominal ultrasonography were enrolled. IAFT was measured sonographically. MetS was defined using NCEP-ATP III criteria, and CKD was classified according to KDIGO 2012 guidelines. Data were analyzed using descriptive statistics, correlation analysis, and multivariate logistic regression. Results: The mean IAFT was 34.8 ± 7.5 mm, higher in males than females (36.2 ± 7.9 vs. 32.8 ± 6.8 mm; p = 0.012). The prevalence of MetS and CKD was 60.1% and 27.7%, respectively, with most CKD cases in early stages (Stage 1–2: 72.3%). IAFT was significantly higher in participants with MetS (38.6 ± 6.9 mm) and CKD (39.2 ± 7.1 mm) compared to those without (29.1 ± 5.4 mm and 32.8 ± 6.7 mm; p < 0.001). IAFT positively correlated with waist circumference (r = 0.61), fasting glucose (r = 0.43), triglycerides (r = 0.37), systolic blood pressure (r = 0.31), and serum creatinine (r = 0.28; all p < 0.01). Multivariate analysis showed IAFT independently predicted MetS (AOR: 2.8; 95% CI: 1.7–4.6; p < 0.001) and CKD (AOR: 2.3; 95% CI: 1.3–4.1; p = 0.003) after adjusting for age, sex, and BMI. Conclusion: Sonographic IAFT is strongly associated with both MetS and CKD, independent of age, sex, and BMI. IAFT may serve as a simple, easily available, cost effective, non-invasive, radiation free mark