DOI: https://doi.org/10.36347/sjmcr.2025.v13i11.022

Pages: 2753-2756

Central neurocytoma is a rare neuroepithelial tumor, accounting for less than 1% of all intracranial neoplasms. It is most frequently located in the lateral ventricles, near the foramen of Monro, and usually manifests with signs of increased intracranial pressure or visual disturbances. Psychiatric onset is exceptional and can lead to diagnostic delay. We report the case of a 34-year-old man with no previous psychiatric history who presented with recent behavioral and mood disturbances suggestive of a manic episode. Despite appropriate pharmacological treatment, symptoms persisted, prompting brain MRI, which revealed a left intraventricular mass measuring 3.5 cm. Surgical resection achieved complete removal, and histopathological examination confirmed a central neurocytoma (WHO grade II). The postoperative course was favorable, with full remission of psychiatric symptoms. This case illustrates how a benign brain lesion can mimic a primary psychiatric disorder, emphasizing the need for neuroimaging in atypical or treatment-resistant psychiatric presentations. A multidisciplinary approach between psychiatry, neurology, and neurosurgery is essential for early diagnosis and optimal outcomes [1–4].