DOI: https://doi.org/10.36347/sjams.2025.v13i12.006

Pages: 1992-1995

Background: Wound healing has been intensively explored in order to find a "ideal" treatment that achieves rapid recovery while minimizing scarring, hence preserving function. Aim of the study: The goal of this study was to evaluate wound healing time and infection control measures. Methods: This observational study was conducted for six months at the Department of Surgery, Sir Salimullah Medical College, and Mitford Hospital in Dhaka. Patients who had superficial surgical site infections after surgery were included in the study. After screening, 200 patients were included. Following the dressing, the topical drug (L-lysine HCL 15% gel) was administered once on days 3, 8, and 13. All patients were followed for a maximum of two weeks. Data on the patient's demographic profile, wound healing, granulation tissue appearance, and overall outcome were collected and documented on a premade and pretested data collection sheet. The data was analyzed with SPSS (Statistical Package for Social Science) (Trail Version). Results: The study population had an average age of 34.43±8.73, with about equal male and female ratios. At the third post-operative day (POD) after surgery, granulation tissue had not formed in 86% (n=172) of the cases and had only partially formed in 14% (n=28). All of them received a thick layer of L-lysine, and on the eighth postoperative day, 92% (n=184) had produced partial granulation tissue, while 3% (n=6) had reached complete healing. At the 13th POD, 91.5% (n=183) of the patients experienced complete wound healing, while the remainder experienced partial wound healing. The study also assessed patients' satisfaction with wound healing, finding that 91% were satisfied, 4% were very satisfied, and the remainder were unsatisfied with the effect of L-lysine. Conclusion: L-lysine shortens the time it takes for granulation tissue to form and speeds up wound healing. However, additional clinical trials are needed to determine the significance of L-lysin as a po