DOI: https://doi.org/10.36347/sjmcr.2025.v13i12.012

Pages: 2946-2948

Thyroid-associated orbitopathy (TAO), also known as Graves’ orbitopathy, is an autoimmune disorder affecting orbital tissues and may lead to severe complications including optic neuropathy, secondary glaucoma, and corneal damage. We report a case of a 60-year-old woman with Graves’ disease presenting with sight-threatening orbitopathy, manifesting all three complications simultaneously. Ophthalmologic examination revealed bilateral exophthalmos, severe limitation of ocular motility, and a central corneal abscess in the left eye. Imaging confirmed optic nerve compression and a multinodular goiter. Management included intravenous corticosteroid therapy, systemic and topical antibiotics, local hypotensive treatment, frequent ocular lubrication, and tarsorrhaphy, under a multidisciplinary approach involving endocrinology, ophthalmology, and neurosurgery. The patient showed improvement in visual acuity, reduction of inflammatory signs, and partial resolution of exophthalmos. This case highlights the importance of urgent, multidisciplinary management in severe Graves’ orbitopathy to preserve visual function and prevent further complications.