DOI: https://doi.org/10.36347/sjmcr.2025.v13i12.037

Pages: 3047-3051

Tuberculosis (TB) is an extremely serious public health issue in India where the highest number of TB cases is reported worldwide. Maharashtra, one of the most populated and economically important states in India, plays a major role in this national burden. This study makes a thorough academic investigation into the tuberculosis situation in Maharashtra and looks into epidemiological patterns, demographic and socio-economic factors, the increasing problem of drug resistance and the state’s response through the National Tuberculosis Elimination Programme (NTEP). The analysis which is based on data from government reports, international health databases, and recent studies points out urban conglomerates such as Mumbai, particular high-risk groups such as migrants and industrial workers, and the epidemics connection with non-communicable diseases as the epidemic’s main triggers. The conclusion of the paper is that Maharashtra has made great progress in case notification and treatment initiation, but elimination targets can only be met by 2025 through intensified, multi-sectoral efforts such as active case finding in high-risk groups, strong infection control, comprehensive management of drug-resistant TB, and dealing with the social determinants of health. The results emphasize the requirement for a specific, data-driven strategy for TB control in a state where there are huge contrasts between urban wealth and poverty, and between fast economic growth and health inequities that persists.