DOI: https://doi.org/10.36347/sjmcr.2026.v14i02.010

Pages: 215-218

Acute fatty liver of pregnancy (AFLP) is a rare but potentially fatal obstetric emergency that typically occurs during the third trimester or early postpartum period. It may rapidly progress to acute liver failure, severe coagulopathy, and multiorgan dysfunction. The clinical presentation often overlaps with HELLP syndrome, making diagnosis challenging. We report a fatal case of AFLP occurring in the immediate postpartum period after emergency cesarean section for HELLP syndrome. Despite aggressive intensive care management including massive transfusion and plasma exchange therapy, the patient developed refractory multiorgan failure leading to death. This case highlights the diagnostic difficulty, therapeutic limitations, and high mortality associated with fulminant AFLP.