DOI: 10.36347/sasjm.2020.v06i05.001

Pages: 137-141

Introduction: Viral infections, especially those caused by the hepatitis C virus (HCV), hepatitis B and that of human immunodeficiency HIV, are common in patients undergoing chronic hemodialysis. Objectives: to determine the prevalence of anti-HCV, anti-HIV and HBs antigen antibodies in chronic hemodialysis patients in the nephrology and hemodialysis department of the UHC Point G. Methodology: This was a retrospective study, carried out from January 1 to December 31, 2015 in the nephrology and hemodialysis service of the UHC Point G. Were included, all chronic hemodialysis patients for 3 months and more having carried out viral serologies of hepatitis B, C and HIV. Results: We collected 45 patients, the female sex represented 57.8% with a sex ratio of 0.73. The average age was 37.61 years with extremes of 16 and 78 years. The detection of anti HCV, anti HIV and HBs antigen antibodies was positive in 4, 9 and 2 patients, respectively, with prevalence rates of 9%, 20% and 4%, respectively. The prevalence of hepatitis C was higher in patients whose duration on dialysis is between 3-6 years (p = 0.021), (see Table-1). The prevalence of HIV infection was also correlated with the duration of hemodialysis greater than 1 year for HIV (p = 0.010). We found two cases of hepatitis B and C coinfection and one case of hepatitis B and HIV coinfection. Blood transfusion was performed in 95.5% of the patients. On multivariate analysis, there was no statistically significant relationship between blood transfusion and these different viral infections [HCV (p = 0.647), HBV (p = 0.289), HIV (p = 0.752)]. Conclusion: this study has highlighted the frequency of viral infections with hepatitis B, C and HIV in our hemodialysis patients. They must be prevented by rigorous control of the blood transfusion circuit, strict observance of hygiene rules and the recruitment of qualified personnel and in sufficient numbers.