DOI: https://doi.org/10.36347/sjmcr.2026.v14i03.027

Pages: 435-438

Thyroid tuberculosis is a rare clinical entity [1], even in endemic regions. Its presentation as a large plunging (retrosternal) goiter with normal thyroid function is exceptional and may mimic multinodular goiter or thyroid malignancy. We report the case of a 33-year-old woman with no significant past medical history who presented with a voluminous plunging goiter. Total thyroidectomy was performed for compressive symptoms. Histopathological examination revealed multinodular hyperplasia associated with epithelioid granulomatous inflammation and caseous necrosis, consistent with thyroid tuberculosis. This case highlights the diagnostic challenge of thyroid tuberculosis and underlines the importance of histopathological examination in atypical thyroid disease.